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. 2022 Apr 1;132(7):e154422. doi: 10.1172/JCI154422

Figure 3. The HIV-1 proviral landscape changes over time in Tn and memory CD4+ T cell subsets.

Figure 3

Correlation analysis of the relationship between the percentage of (A) intact HIV-1 proviral sequences; (B) 3′ deleted HIV-1 proviral sequences; (C) HIV-1 proviral sequences with an intact gag ORF; and (D) HIV-1 proviral sequences with an intact pol ORF within each participant and time on ART (years) across Tn, Tcm, Ttm, and Tem cells. Each data point represents the percentage of sequences obtained per participant. Statistical significance was calculated by Spearman’s correlation test. P ≤ 0.05 values are shown in red. Tn, naive; Tcm, central memory; Ttm, transitional memory; Tem, effector memory; ORF, open reading frame.