Figure 4. Proportion of HIV-1 proviral sequences expressing CTL WT and unrecognizable epitopes for Gag correlates with time on ART in Tcm CD4⁺ T cells.

Correlation analysis of the relationship between the percentage of HIV-1 proviral sequences harboring WT epitopes, escape variants, and unrecognizable epitopes and time on ART (years) for the viral proteins Gag, across Tn, Tcm, Ttm, and Tem cells. Each data point represents the percentage of sequences obtained per participant. Statistical significance was calculated by Spearman’s correlation test. P ≤ 0.05 values are shown in red. Tn, naive; Tcm, central memory; Ttm, transitional memory; Tem, effector memory.