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. 2022 Apr 1;132(7):e154422. doi: 10.1172/JCI154422

Figure 6. The proportion of HIV-1 proviral sequences with intact nef ORFs is higher in Tem cells.

Figure 6

The percentage of sequences carrying genetically intact ORFs for (A) nef; (B) gag; and (C) pol was quantified across Tn and memory CD4+ T cells using a mixed logistic model. The percentage of HIV-1 proviral sequences harboring genetically intact gag (D) or pol (E) in combination with genetically intact nef within Tn and memory CD4+ T cells is shown. Data represent the adjusted overall percentage ± 95% CI. P values were calculated with a likelihood ratio test. Tn, naive; Tcm, central memory; Ttm, transitional memory; Tem, effector memory; ORF, open reading frame. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001.