Table 4.
Association between haplotypes of three candidate genes and PCa.
| Gene | Haplotype | Cases | Controls | OR (95% CI) | p |
|---|---|---|---|---|---|
| GATA2 | A-C-G | 107 (45.5%) | 121 (48.0%) | 0.853 (0.685-1.573) | 0.247 |
| A-T-G | 82 (34.9%) | 94 (37.3%) | 1.158 (0.835-1.867) | 0.083 | |
| G-C-A | 31 (13.2%) | 18 (7.14%) | 1.642 (1.236-2.768) | 0.001 | |
| A-C-A | 6 (2.55%) | 10 (3.97%) | 0.854 (0.638-1.769) | 0.125 | |
| ZMIZ1 | A-A-G | 54 (22.9%) | 71 (28.2%) | 0.569 (0.427-0.874) | <0.01 |
| A-G-G | 53 (22.5%) | 62 (24.6%) | 0.876 (0.644-1.527) | 0.254 | |
| G-A-G | 44 (18.7%) | 46 (18.2%) | 1.023 (0.856-1.735) | 0.538 | |
| A-A-A | 21 (8.94%) | 27 (10.7%) | 0.956 (0.628-1.837) | 0.633 | |
| G-A-A | 19 (8.08%) | 18 (7.14%) | 1.201 (0.953-1.674) | 0.573 | |
| G-G-G | 21 (8.94%) | 8 (3.17%) | 1.572 (1.248-2.639) | <0.01 | |
| SUN2 | A-T-C | 65 (27.7%) | 74 (29.4%) | 0.875 (0.673-1.864) | 0.363 |
| C-C-T | 42 (17.9%) | 48 (19.1%) | 0.924 (0.735-1.739) | 0.246 | |
| A-C-C | 41 (17.4%) | 42 (16.7%) | 1.183 (0.679-1.536) | 0.537 | |
| A-C-T | 33 (14.0%) | 34 (13.5%) | 1.045 (0.842-1.731) | 0.438 | |
| A-T-T | 31 (13.2%) | 32 (12.7%) | 1.039 (0.742-1.825) | 0.383 |
GATA2, order of SNPs: rs73862213-rs2335052-rs10934857. ZMIZ1, order of SNPs: rs704017-rs77911174-rs3740259. SUN2, order of SNPs: rs78397383-rs5750680-rs138705.