Table 2.
Baseline characteristics of AIS patients and control subjects.
| AIS patients (n = 166) | Control subjects (n = 83) | P value | |
|---|---|---|---|
| Age (year), mean ± SD | 56.98 ± 0.83 | 55.86 ± 1.28 | 0.447 |
| Male, n (%) | 115 (69.3) | 56 (67.5) | 0.772 |
| Medical history, n (%) | |||
| Hypertension | 103 (62.0) | 36 (43.3) | 0.005 |
| Diabetes | 31 (18.7) | 13 (15.7) | 0.557 |
| Hyperlipidemia | 12 (7.2) | 10 (12.0) | 0.207 |
| Smoking | 84 (50.6) | 38 (45.8) | 0.473 |
| Alcohol abuse | 61 (36.7) | 27 (32.5) | 0.512 |
| Laboratory findings, median (IQR) | |||
| Total cholesterol | 4.1 (3.5-4.7) | 4.1 (3.4-4.9) | 0.909 |
| Triglycerides | 1.3 (1-1.7) | 1.4 (1-1.7) | 0.823 |
| LDL-C | 2.6 (2-3.1) | 2.4 (1.8-3.2) | 0.917 |
| HDL-C | 1 (0.8-1.2) | 1 (0.8-1.2) | 0.43 |
| Serum creatinine | 71 (61-82.8) | 68 (59-77.5) | 0.164 |
| Uric acid | 314.9 (259.8-365.9) | 308.6 (248.1-386.2) | 0.911 |
| C-reactive protein | 2.3 (1.1-5.4) | 1 (0.6-2.4) | <0.001 |
| Homocysteine | 13.9 (11.6-19.2) | 11.2 (8.7-16.7) | 0.002 |
| Fibrinogen | 3.3 (2.9-4) | 3 (2.6-3.6) | 0.016 |
| Proteinuria, n (%) | 33 (19.9) | 6 (7.2) | 0.01 |
| White matter hyperintensities, n (%) | 0.003 | ||
| Fazekas 0 | 15 (9) | 17 (20.5) | |
| Fazekas 1 | 79 (47.6) | 48 (57.8) | |
| Fazekas 2 | 46 (27.7) | 11 (13.3) | |
| Fazekas 3 | 26 (15.7) | 7 (8.4) | |
AIS: acute ischemic stroke; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.