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. 2022 Mar 24;2022:7955290. doi: 10.1155/2022/7955290

Table 3.

Summary of characteristics of initial excision patients.

Variables Total LLETZ Cold knife cone (CKC) Diathermy ablation p value across 3 treatment groups
Number of patients 155 144 (92.9%) 5 (3.2%) 6 (3.9%)
Median age at referral in years (range) 28 (22–65) 28 (22–63) 42 (29–65) 24 (22–29) 0.003
Smoking
 Yes 56 (100%) 51 (91.1%) 2 (3.6%) 3 (5.3%) 0.502
 No 90 (100%) 85 (94.4%) 3 (3.3%) 2 (2.2%)
 Not available 9 (100%) 8 (88.9%) 0 1 (11.1%)
Excisional margins
Endocervical margin 0.234
 Not involved 132 (88.6%) 129 (89.6%) 3 (60%) N/A
 Involved 9 (6.0%) 8 (5.6%) 1 (20%) N/A
 Not available 8 (5.4%) 7 (4.8%) 1 (20%)
Ectocervical margin >0.999
 Not involved 102 (68.5%) 99 (68.8%) 3 (60%) N/A
 Involved 38 (25.5%) 37 (25.7%) 1 (20%) N/A
 Not available 9 (6.0%) 8 (5.5%) 1 (20%)
Radial Margin >0.999
 Not involved 117 (78.5%) 113 (78.5%) 4 (80%) N/A
 Involved 9 (6.0%) 9 (6.3%) 0 N/A
 Not available 23 (15.4%) 22 (15.3%) 1 (20%)
Overall Margin 0.615
 Not involved 93 (64.6%) 91 (65%) 2 (50%) N/A
 Involved 51 (45.4%) 49 (35%) 2 (50%) N/A
TOC 0.049
 Yes 123 (79.4%) 116 (80.6%) 3 (60%) 4 (66.7%)
 No 32 (20.6%) 28 (19.4%) 2 (40%) 2 (33.3%)
Cure rates 6 months posttreatment 73.2% (90/123) 72.4% (84/116) 66.7% (2/3) 100% (4/4)
Overall cure rates (as of July 2019) 89.4% (110/123) 88.8% (103/116) 100% (3/3) 100% (4/4) 0.805
Median interval between referral and discharge (months) (range) 11.7 (2.9–74.8) 11.4 (2.9–74.8) 15.7 (8.8–40.2) 16.8 (13.5–29.6) 0.286
Median number of visits prior to discharge (range) 3 (2–8) 3 (2–8) 6 (3–8) 3 (3–4) 0.021