TL20
|
TL at age 20 years (kb) |
TLX
|
TL at x years older than 20 years (kb) |
TLB
|
Telomeric brink, stopping cell replication (5 kb) |
TLO
|
TL at onset of clone size limitation (6.4 kb) |
XO
|
Age in years when TL0 is reached |
CS |
Clone Size |
MCS |
Maximal Clone Size (∼ 106 T cells) |
LCS |
Limited Clone Size (< MCS) |
Δmax
|
TL shortening required for achieving MCS (∼ 1.4 kb) |
g |
TL shortening rate with age (∼ 0.03 kb/year) |
r |
TL shortening rate per T-cell replication (∼ 0.07 kb) |
N |
Number of T-cell replications in LCS (after TLO, XO) |
Nmax
|
Number of T-cell replications in MCS (before TLO, XO) |