Table 2.

Factors associated with fibrosis over time, as measured by the APRI score (Mixed-effect model)

Regression coefficients	Coefficient	95% CI	p-value
Fixed effect
Examination	–0.005	–0.009, –0.001	<0.001
Age	0.013	0.005, 0.0219	<0.001
Gender
Female	ref	ref	ref
Male	0.011	–0.148, 0.364	0.408
Education level
Secondary school	ref	ref	ref
High school	–0.180	–0.509, 0.148	0.281
University/College	0.066	–0.206, 0.338	0.635
Postgraduate	–0.201	–0.982, 0.581	0.615
Job
Working	ref	ref	ref
Non-working	–0.054	–0.108, 0.001	0.05
Time for disease detection (years)	–0.012	–0.030, 0.007	0.218
Drinking tea
No	ref	ref	ref
Yes	–0.085	–0.350, 0.181	0.533
Forget to take medicine
No	ref	ref	ref
Yes	–0.002	–0.246, 0.242	0.988
Audit score	0.011	–0.032, 0.054	0.614
Random effect	Variance	95% CI
APRI patients variance	0.0001	0.000, 0.002
Baseline APRI of patients variance	0.1965	0.130, 0.297

APRI: aspartate aminotransferase (AST)/platelet ratio index

ref: reference group

CI: confidence interval