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. 2022 Apr 1;40(20):2848–2855. doi: 10.1016/j.vaccine.2022.03.064

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© 2022 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 3 — Viral loads detected in hamster nasal wash by plaque assay and E gene qPCR. Infectious titres measured by plaque assay in Vero cells are indicated by lines. Viral RNA loads measured by qRT-PCR for E gene are indicated by histogram bars for each individual hamster n = 6 per group. (a) B.1.238 infected donors. (b) saRNA SARS-CoV-2 S vaccinated hamsters exposed to B.1.238 donors. (c) saRNA influenza H1 HA vaccinated hamsters exposed to B.1.238 donors. (d) B.1.1.7 infected donors. (e) saRNA SARS-CoV-2 S vaccinated hamsters exposed to B.1.1.7 donors. (f) saRNA influenza H1 vaccinated hamsters exposed to B.1.1.7 donors.