Table 2.
Publication summaries.
Author/Pub Info | Aims | Sample - Setting, Time of data collection, and considerations | Results | Vaccine hesitancy or attitudes |
---|---|---|---|---|
Abohelwa, M. et al.27 Primary authors discipline: Medicine Article |
To understand residents and fellows’ attitudes toward vaccination and record any side-effects after vaccination | 81 residents and fellows South March 2021 |
77 (95.1%) accepted 3 (3.7%) refused Other findings: All 77 vaccinated reported pain at the injection site and headache in 49.4% |
78 (96.3%) of the sample reported that they supported vaccination |
Ciardi, F. et al.28 Primary authors discipline: Medicine Article |
This study was conducted about attitudes toward COVID-19 vaccination among healthcare workers at a public hospital in New York City during the beginning of COVID-19 vaccination | 428 hospital workers∗ ∗physicians (28.5%), nurses (21.96%) Northeast December 2020 to January 2021 |
274 (64%) accepted 38 (8.9%) intended 116 (27%) refused Statistically significant correlations Gender: Males < hesitant Age: Older (65+) < hesitant Race: Asian least hesitant, Black most hesitant Ethnicity: Hispanic > hesitancy Other significant associations: Role within hospital, use of PPE, and perceived personal risk |
The most predictive factors were prior vaccine attitudes and concern with the speed of testing and approval of the vaccines |
Famuyiro, T. B. et al.29 Primary authors discipline: Medicine Article |
To assess the readiness for vaccine uptake among HCWs at three community-based, university-affiliated health centers | 205 community-based workers∗ ∗physicians (40.5%), other clinical staff (44.4%) South December 2020 |
110 (54%) immediate intention 56 (27%) waiting 36 (18%) had no intention Statistically significant correlations: Gender: Males < hesitant Age: Older (65+) < hesitant Race: Asian least hesitant Black > hesitant than White Ethnicity: Hispanic > hesitant than White Other significant associations: moderate-risk perception < hesitance than those with low-risk perception |
Most physicians (83%) and residents (81%) expressed more enthusiasm to receive the vaccine once it became available compared with other clinical staff (nurses, medical assistant, clinical technician, etc.; 31%) |
Fontenot, H.B. et al.30 Primary authors discipline: Nursing Article |
To assess the intentions of licensed nurses in the State of Hawaii to obtain a COVID-19 vaccine and identify factors that are associated with nurses’ intention to vaccinate | 423 nurses West December 2020 |
221 (52%) intended 118 (27.9%) waiting 84 (19.9%) had no intention Statistically significant correlations: Age: Older (50+) < hesitant |
The strongest predictors of any level of intention were greater positive attitudes toward COVID-19 vaccination and lower concerns related to COVID-19 vaccine safety |
Fossen, M. C. et al.38 Primary authors discipline: Nursing Letter |
Examined vaccination rates of hospital workers by age, gender, department, and race to determine in which groups vaccine hesitancy was highest | 3401 hospital workers South March 2021 |
2245 (71%) accepted 976 (29%) refused Statistically significant correlations: Age: Older (50+) < hesitant Race: Black > hesitancy than White Other significant associations: Working in a clinical department < hesitancy |
|
Gadoth, A. et al.39 Primary authors discipline: Public Health Letter |
To understand general vaccine acceptance and specific attitudes toward forthcoming coronavirus vaccines among HCWs in Los Angeles, California | 540 healthcare workers∗ ∗prescribing clinicians 37.2%, registered nurses 38.3% West September to October 2020 |
179 (33%) immediate intention 354 (65.6%) waiting 7 (1.3%) had no intention Correlations (p values unknown): Age: Older (51+) < hesitant Race: Asian > hesitant than White Ethnicity: Hispanic > hesitant Other findings: Prescribing clinicians exhibited 20–30% less hesitant than other HCWs |
46.9% of questioned the efficacy of vaccine Fast-tracking regulatory procedures and a lack of transparency were primary rationales for refusal or delay |
Grumbach, K. et al.40 Primary authors discipline: Medicine Letter |
Investigated COVID-19 vaccine intentions among racially and ethnically diverse samples of HCW and the general population | 1803 healthcare workers∗ ∗physicians, APPs and registered nurses (76.7%) West November 2020 to January 2021 |
1507 (83.6%) intended Statistically significant correlations: Race: White was least hesitant Asian > hesitant Black > hesitant (most hesitant) Multiple/other > hesitant Ethnicity: Hispanic > hesitant |
Black, Latinx, and Asian respondents reported less confidence in vaccine efficacy, less trust in companies making the vaccine, and more worry that government rushed the approval process |
Halbrook, M. et al.31 Primary authors discipline: Public Health Article |
The primary outcome of interest was COVID-19 vaccination intent and vaccine uptake among HCW | 858 healthcare workers∗ ∗Advanced degree (59.8%) West September 2020 to February 2021 |
281 (32.8%) intended at survey 1 566 (68.8%) intended/accepted at survey 2 823 (96%) accepted at survey 3 Statistically significant correlations: Age: Older (50+) < hesitant Race∗: Black > hesitancy than White Asian > hesitant than Black and White ∗This relationship is seen with intention but not uptake Other significant associations: Educational attainment was associated with intention and uptake |
Among HCWs refusing the vaccine reasons included not having enough information or belief that the vaccine could infect them with COVID-19 |
Kociolek, L. et al.41 Primary author's discipline: Medicine Letter |
Assessing frequency of vaccine hesitancy, characteristics of those reporting vaccine hesitancy, specific concerns, and communication preferences among hospital workers | 4448 hospital workers Midwest December 2020–January 2021 |
368 (8.6%) accepted 2559 (59.8%) intended 810 (18.9%) hesitant Statistically significant correlations: Gender: Males < hesitant Race: Black > hesitant than non-Black Ethnicity: Hispanic > hesitant Other significant associations: Hesitancy was associated with less concern about personal risk of severe COVID-19 and (three times) more prevalent in those with high-risk medical conditions. |
Concerns reported were vaccine safety related to novelty and speed of the clinical development process |
Kuter, B. J. et al.32 Primary author's discipline: Public Health Article |
To understand attitudes toward COVID-19 vaccines… to obtain a better understanding of how hospital employees, both in clinical and non-clinical positions, perceive the new COVID-19 vaccines and their intention to be vaccinated | 12,034 hospital workers Northeast November to December 2020 |
7492 (63.7%) intended 4368 (36.3%) hesitant Statistically significant correlations: Gender: Males < hesitant Age: Older (65+) < hesitant Race: Black > hesitant than White Asian < hesitant Ethnicity: Hispanic > hesitant Other significant associations: Less hesitancy in those with up-to-date vaccinations, good-excellent self-reported health and no direct patient contact |
Over 80% of vaccine hesitant reported concerns over side-effects and vaccines’ newness 78% of hesitant reported not knowing enough of about the vaccine 33% questioned efficacy and 25% were concerned about getting COVID-19 from the vaccine |
Meyer, M. N. et al.42 Primary author's discipline: Bioethics Letter |
To assess their intentions to [receive a COVID-19 vaccination], and understand reasons for hesitancy among HCW | 16,292 healthcare workers Northeast December 2020 |
9015 (55.3%) intended 7277 (44.6%) hesitant Significant associations: Patient-facing employees were less hesitant than those who do not interact with patients |
90.3% of vaccine hesitant reported concerns about unknown risks of the vaccines, 44.3% reported they wanted to wait until others’ vaccine experiences are known, and 21.1% reported that they do not trust the rushed FDA process. |
Pacella-LaBarbara, M. et al.33 Primary author's discipline: Health psychology Article |
To determine vaccine intent/uptake, perceived COVID-19 vulnerability, and factors associated with vaccine intent/uptake. | 475 emergency department and EMS workers Mid-Atlantic January 2021 |
337 (79%) accepted or intended 98 (21%) had no intention Statistically significant correlations: Gender: Males < hesitant Other significant associations: Those with a history of COVID-19 infection had lower intention Those with an advanced degree had higher intention/uptake (zero physicians reported no intention) |
Those with a higher perceived COVID-19 vulnerability had higher rates of intention or uptake |
Pamplona, G. M. et al.43 Primary author's discipline: Unknown Letter |
To report dialysis staff vaccination acceptance and hesitancy rates from four Renal Research Institute dialysis clinics and a home dialysis program located in New York, New York. | 157 community-based healthcare workers Northeast January 2021 |
115 (73.2%) accepted 6 (3.8%) hesitant 36 (23%) waiting/unknown intent Other findings: Reasons for delay included: recent COVID-19 infection, leave of absence from work, and pregnancy or breastfeeding |
|
Parente, D. J. et al.34 Primary author's discipline: Medicine Article |
To evaluate HCW willingness to become vaccinated against COVID-19 and identified barriers/facilitators to vaccine uptake among all personnel at a large academic medical center in the Midwest | 3347 healthcare workers Midwest August 2020 |
1241 (37%) intended 1764 (52%) waiting 331 (10%) had no intention Statistically significant correlations: Gender: Males < hesitant Race: Black > hesitant than White Other significant associations: Prior influenza vaccination, increased concern about COVID-19, and postgraduate education were associated with vaccine acceptance |
Barriers to vaccination included concerns about long-term side-effects (57.1%), safety (n = 55.0%), efficacy (37.1%), and risk-to-benefit ratio (31.0%) |
Schrading, W. A. et al.44 Primary author's discipline: Medicine Letter |
To describe differences in vaccination rates among various types of ED HCP at US academic medical centers and reasons for declining vaccination | 1321 Emergency Department hospital workers∗ ∗physicians/APP 49.4%, registered nurses 25.75% Multiple US regions January 2021 |
Results: 1136 (86%) received vaccine Correlations (p value unknown): Non-Hispanic Black HCWs had the lowest vaccine acceptance rate Other findings: Physicians and APPs had the lowest refusal rate (5.5% of 674), compared with nurses (22.3% of 345) and non-clinical HCWs (23.5% of 302) Vaccinated recipients planned to use the same amount of PPE at work as well as in public |
The primary reason for declining a COVID-19 vaccine was concern about vaccine safety (45.4%) |
Shaw, J. et al.35 Primary author's discipline: Medicine Letter |
To provide a snapshot of vaccination attitudes in order to identify areas of concern that would impinge on COVID-19 vaccination program planning and implementation | 5287 hospital workers North East November to December 2020 |
3032 (57.5%) intended 2245 (42.5%) hesitant Statistically significant correlations: Gender: Males < hesitant Age: Older (65+) < hesitant Race: Asian least hesitant Black > hesitant than White Other significant associations: 80.4% of physicians and scientists intended to get vaccinated, compared with 51.4% of allied health professionals and 41.2% of nurses More non–care providers indicated they would take the vaccine if offered |
Vaccine safety, potential adverse events, efficacy, and speed of vaccine development dominated concerns listed by participants |
Shekhar, R. et al.36 Primary author's discipline: Medicine Article |
To assess the attitude of HCWs toward COVID-19 vaccination | 3479 healthcare workers ∗professional or graduate degree 32.5%, Multiple regions October–November 2020 |
1247 (36%) intended 1953 (56%) waiting 279 (8%) had no intention Statistically Significant Correlations Gender: Males < hesitant Age: Older (60+) < hesitant Race: Asian least hesitant Black > hesitant than White Ethnicity: Hispanic > hesitant Other significant associations: HCWs working in rural areas had more hesitancy Direct medical care providers, those with professional or doctoral degrees and those with prior flu vaccination had higher intention |
Safety (69%), effectiveness (69%), and speed of development/approval (74%) were noted as the most common concerns regarding COVID-19 vaccination in our survey |
Unroe, K. T. et al.37 Primary author's discipline: Medicine Article |
To plan for coronavirus infectious disease 2019 (COVID-19) vaccine distribution, the Indiana Department of Health surveyed nursing home and assisted living facility staff. | 8243 long-term care staff Midwest November 2020 |
3704 (45%) intended 2001 (24%) waiting 2523 (31%) had no intention Statistically significant correlations: Gender: Males < hesitant Age: Older (60+) < hesitant Race: Black > hesitant Other significant associations: Clinical care staff, including nurse aides and nurses in clinical roles, were less likely than dietary, housekeeping, and administrative staff to report willingness to receive the vaccine Nurses providing direct clinical care were −5 percentage points less likely to indicate a willingness to take the vaccine than nurse aides or similar role |
Concerns about side-effects was the primary reason for vaccine hesitancy (70%) other non-mutually exclusive reasons given were health concerns (34%), questioning the effectiveness (20%), and religious reasons (12%). In addition, 23% of respondents provided other reasons they would be unwilling to receive the vaccine such as concerns it is “too new,” a lack of trust, the need for more research, or it was too political |
FDA, Food and Drug Administration; HCW, healthcare workers.