Impact of RDI Levels of FOLFOX Chemotherapy on All-Cause Mortality and Cancer-Specific Mortality in High-Risk Stage III Colon Cancer—Univariable Analysis.
| All-cause mortality (N=168) |
Cancer-specific mortality (N=160) |
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|---|---|---|---|---|---|
| RDI | Low RDI% (RDI<selected cutoffs | Crude HR (95% CI) | P | Crude HR (95% CI) | P |
| RDI< 55% vs. RDI≥ 55% | 20.8 | 3.91 (1.97, 7.78) | <.0001 | 3.79 (1.59, 9.03) | 0.003 |
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| RDI< 60% vs. RDI≥ 60% | 27.4 | 2.86 (1.44, 5.69) | 0.003 | 2.73 (1.16, 6.42) | 0.02 |
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| RDI< 65% vs. RDI≥ 65% | 31.6 | 2.39 (1.20, 4.76) | 0.01 | 2.18 (0.93, 5.11) | 0.07 |
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| RDI< 70% vs. RDI≥ 70% | 39.9 | 1.57 (0.79, 3.11) | 0.2 | 1.29 (0.55, 3.03) | 0.56 |
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| RDI< 75% vs. RDI≥ 75% | 47.6 | 1.78 (0.88, 3.58) | 0.11 | 1.51 (0.65, 3.53) | 0.34 |
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| RDI< 80% vs. RDI≥ 80% | 58.9 | 1.37 (0.66, 2.82) | 0.4 | 1.26 (0.52, 3.06) | 0.62 |