Table 2.
SUCRA | Hospitalization for HF or CV death | All-cause mortality | CV mortality | Hospitalization for HF | Worsening RF | Worsening RF or CV death |
---|---|---|---|---|---|---|
Canagliflozin | 0.708 | 0.691 | 0.726 | 0.752 | 0.565 | 0.412 |
Dapagliflozin | 0.432 | 0.611 | 0.608 | 0.337 | 0.442 | n.a. |
Empagliflozin | 0.425 | 0.386 | 0.503 | 0.347 | 0.672 | 0.439 |
Ertugliflozin | 0.243 | n.a. | n.a. | 0.473 | n.a. | n.a. |
Licogliflozin | n.a. | 0.559 | 0.347 | n.a. | n.a. | n.a. |
Placebo | 0.041 | 0.192 | 0.251 | 0.020 | 0.082 | 0.403 |
Sitagliptin | 0.809 | 0.558 | 0.550 | 0.819 | 0.739 | 0.671 |
Sotagliflozin | 0.842 | 0.504 | 0.515 | 0.751 | n.a. | n.a. |
SUCRA is a transformation of the mean rank that accounts both for the location and the variance of all relative treatment effects. The larger the SUCRA value, the better the rank of the treatment [20]
CV cardiovascular, HF heart failure, n.a. not available, RF renal function