TABLE 3.
Multivariable Cox regression model of risk factors associated with death, graft loss, or death-censored graft loss.
| Death | Graft loss | Death-censored graft loss | ||||
|---|---|---|---|---|---|---|
| HR (95%CI) | p | HR (95%CI) | p | HR (95%CI) | p | |
| Plasma oxalate >13.0 μmol/L | 2.23 (1.24–4.01) | 0.008 | 1.80 (1.09–2.97) | 0.021 | 1.68 (0.78–3.64) | 0.188 |
| Recipient age (years) | 1.08 (1.06–1.11) | <0.001 | 1.03 (1.01–1.05) | 0.001 | ||
| Donor > 60 years | 1.13 (0.55–2.32) | 0.731 | 1.50 (0.80–2.81) | 0.205 | 3.00 (1.27–7.08) | 0.012 |
| Living donor | 0.36 (0.18–0.70) | 0.003 | 0.43 (0.26–0.72) | 0.001 | 0.45 (0.21–0.93) | 0.032 |
| HLA-DR mismatch (1 or 2) | 1.10 (0.65–1.85) | 0.718 | 1.81 (1.12–2.93) | 0.015 | 3.64 (1.47–9.01) | 0.005 |
| mGFR at 10 weeks (ml/min) | 1.00 (0.99–1.02) | 0.727 | 0.99 (0.98–1.01) | 0.401 | 0.99 (0.97–1.01) | 0.471 |
| Current smoker at 10 weeks | 3.10 (1.69–5.68) | <0.001 | 1.96 (1.15–3.35) | 0.014 | 0.67 (0.20–2.25) | 0.516 |
Abbreviations: HLA-DR, Human Leukocyte Antigen-DR; mGFR, measured glomerular filtration rate. Bold data indicate statistical significant findings.