Table 4.
Association of early menopause and all-cause mortality by Cox proportional hazard regression models among CKD group.
| Groups | Model la HR | P value | C-index | Model IIb HR | P value | C-index | Model IIIc HR | P value | C-index |
|---|---|---|---|---|---|---|---|---|---|
| Women with natural menopause | |||||||||
| Natural menopause at age ≧45 | Ref (1.00) | Ref (1.00) | Ref (1.00) | ||||||
| Early natural menopause | 1.25 (0.96–1.63) | 0.095 | 0.64 (0.58–0.65) | 1.20 (0.92–1.57) | 0.177 | 0.69 (0.66–0.72) | 1.22 (0.93–1.60) | 0.158 | 0.73 (0.70–0.76) |
| Women with surgical menopause | |||||||||
| Surgical menopause at age ≧45 | Ref (1.00) | Ref (1.00) | Ref (1.00) | ||||||
| Early surgical menopause | 1.10 (0.74–1.63) | 0.640 | 0.62 (0.56–0.68) | 1.40 (0.94–2.08) | 0.096 | 0.73 (0.68–0.78) | 1.25 (0.81–1.92) | 0.317 | 0.76 (0.71–0.81) |
a
Adjusted for eGFR and UACR.
b
Adjusted for age, race/ethnicity, eGFR, and UACR.
c
Adjusted for age, race/ethnicity, eGFR, UACR, marital status, smoke, alcohol use, obesity, triglycerides (mg/dl), total cholesterol (mg/dl), HDL-cholesterol (mg/dl), hypertension, diabetes, coronary heart disease, congestive heart failure, stroke, cancer.