Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 31;13(3):288. doi: 10.1038/s41419-022-04744-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — A Differentially expressed genes between AMTB 30 μM treatment and control group, with fold change ≥ 2 and p value ≤ 0.05. B Heatmap colored according to the expression PFKM value, showing all of the differentially expressed genes involved in proliferation and metastasis. The red represent genes that are upregulated, and the blue represent genes that are downregulated. THBS1, INHBA, TGFB2, and NOG, primary KEGG enrichment members of this pathway, are indicated. C KEGG pathway analysis revealed a downregulation of TGFβ signaling after treatment with AMTB 30 μM in osteosarcoma cells.