Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 31;13(3):288. doi: 10.1038/s41419-022-04744-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — A IC50 values of U2OS cells and 143B cells after incubation with cisplatin for 48 h. B Combination of various concentrations of AMTB and cisplatin were used to treat osteosarcoma cells, and the results indicated that AMTB combined with low dosage of cisplatin exhibited stronger suppressive effect compared with high dosage of cisplatin alone. The data was compared by two-way ANOVA with Bonferroni test and shown as mean ± s.d. ***P < 0.001. C Preclinical experimental model of osteosarcoma induced by subcutaneous injection of osteosarcoma cells into the back of the mice. n = 6. D Tumor volume was recorded every two days after indicated treatment, and tumors were removed and weighted at the termination of the study. The data was compared by two-way ANOVA with Bonferroni test and shown as mean ± s.d. ***P < 0.001. E The isolated xenograft tumors from treated or control group were shown. n = 6. F Vital organs amongst different treatment groups were weighted and showed no significant difference. H&E staining of vital organs amongst different treatment groups indicated that no histologic changes were induced by ATMB treatment. The data was compared by one-way ANOVA with Tukey’s multiple comparison test and shown as mean ± s.d. **P < 0.01, ***P < 0.001.