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. 2022 Mar 31;12:5451. doi: 10.1038/s41598-022-09270-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Representative examples of possible search strategies. Search strategies used by mice to locate the hidden platform can be divided into hippocampus-dependent and not hippocampus-dependent strategies. Pathfinder categorizes each trial according to 1 of 8 possible strategies. Spatial strategies include ‘direct path’, ‘directed search’, ‘focal search’ and ‘indirect search’. ‘Chaining’, ‘scanning’, ‘random search’ and ‘thigmotaxis’ are considered as non-spatial strategies.