Table 1.
Molecular targets | Biological function | References |
---|---|---|
FOXO3a, OPA1 | Mitochondrial dynamics | (43, 44) |
OGG1 | Mitochondrial DNA repair | (40) |
MnSOD | ROS homeostasis | (45) |
Ku70 | Cell Survival | (26) |
CypD | Mitochondrial structure and function | (46) |
p53 | Glucose metabolism | (47) |
PDC | Glucose metabolism | (48) |
TCA enzymes (citrate synthase, aconitase, isocitrate dehydrogenase, succinate dehydrogenase, malate dehydrogenase) | Glucose metabolism | (39, 49–52) |
ETC enzymes (succinate dehydrogenase, NDUFA9 subunit of complex I) | ATP production | (37) |
HMG Co-A synthase | Ketogenesis | (53) |
Glutamate dehydrogenase | Amino acid metabolism | (36) |