Table 4.

Multivariate linear regression analysis of the association between the change in assessed variables within both experimental and control groups.

Variables	Experimental group				Control group
	HOMA-IR index		Depression scores		HOMA-IR index		Depression scores
	Β	P –value	Β	P –value	Β	P –value	Β	P –value
Estradiol hormone (Pg/ml)	0.042	0.823	0.279	0.118	0.038	0.853	0.105	0.593
Total testosterone hormone (ng/ml)	0.093	0.570	-0.235	0.187	-0.033	0.871	0.212	0.284
Free testosterone hormone (pg/ml)	-0.151	0.447	-0.094	.648	0.038	0.852	0.100	0.609
SHBG hormone (nmol/ml)	-0.630	0.014∗	-0.414	0.062	-0.001	0.995	-0.101	0.606
Regression equation (R2)	0.377		0.264		0.004		0.072
P –value	0.004∗		0.093		0.999		0.746

β: Standardized regressions Coefficients.

∗: Statistically significant at p < 0.05 according to Multivariate linear regression analysis.

SHBG: Sex Hormone Binding Globulin. HOMA-IR index: Homeostatic Model Assessment for Insulin Resistance.