Table 2.
Comparison of observed and predicted mortality. Predicted mortality estimated by the APACHE II score was overestimated compared to the observed mortality determined by the Kaplan-Meier estimator at survivors’ mean hospital stay. Results are given for the total cohort as well as for patients with CS-complicating acute myocardial infarction. Furthermore, subgroup analyses for both cohorts are displayed. An adjusted Diagnostic Category Weight was calculated by using survival data from the Dresden Impella Registry and the formula created by Knaus et al. [6] if the difference between the observed and predicted mortality achieved significance. APACHE, Acute Physiology and Chronic Health Evaluation; CPR, cardiopulmonary resuscitation; CAD, coronary artery disease; ACS, acute coronary syndrome; IHCA, in-hospital cardiac arrest; OHCA, out-of-hospital cardiac arrest; NSTEMI, non-ST-segment elevation myocardial infarction; STEMI, ST-segment elevation myocardial infarction; LMS, left main stem; LAD, left anterior descending; RCX, ramus circumflexus; RCA, right coronary artery.
| Parameter | Sub-category |
APACHE II score mean + SEM; (n) |
Survivors’ length of hospital stay [thosp]/ d mean + SEM; (n) |
Mortality at survivors’ mean hospital stay/% ± SE(; (n) |
Predicted Mortality by APACHE II score / % mean + SEM; (n) |
p-Wert | Adjusted Diagnostic Category Weight | |
|---|---|---|---|---|---|---|---|---|
| All patients | 33.5 ± 0.6; (180) | 22.9 ± 1.6; (71) | 54.4 ± 3.7; (180) | 74.6 ± 1.6; (180) | <0.001 | −1,183 | ||
|
CPR |
No CPR | 30.2 ± 0.8; (91) | 23.7 ± 2.0; (44) | 46.2 ± 5.2; (91) | 0.004 | 61.9 ± 2.3; (91) | 0.037 | −1,044 |
| CPR | 36.8 ± 0.7; (89) | 21.6 ± 2.6; (27) | 62.9 ± 5.1; (89) | 87.5 ± 1.3. (89) | <0.001 | −1,328 | ||
| Serum lactate | 4–4.9 mmol/l | 29.2 ± 1.0; (60) | 21.8 ± 2.2; (38) | 30.0 ± 5.9; (60) | <0.001 | 61.5 ± 3.0; (60) | <0.001 | −1,593 |
| 5–10 mmol/l | 33.6 ± 1.1; (43) | 22.3 ± 3.6; (14) | 60.5 ± 7.5; (43) | 75.8 ± 3.2; (43) | 0.104 | −0,962 | ||
| >10 mmol/l | 37.3 ± 0.7; (68) | 27.3 ± 2.4; (16) | 70.6 ± 5.5; (68) | 85.8 ± 1.7; (68) | 0.039 | −1,053 | ||
| Only acute myocardial infarction patients (n = 120) | ||||||||
| All patients | 33.9 ± 0.7; (120) | 22.3 ± 1.9; (47) | 54.2 ± 4.5; (120) | 76.3 ± 1.9; (120) | <0.001 | −1,264 | ||
| CPR | No CPR | 30.4 ± 1.0; (53) | 22.5 ± 2.4; (26) | 45.3 ± 6.8; (53) | 0.020 | 62.8 ± 2.9; (53) | 0.080 | / |
| CPR | 36.6 ± 0.8; (67) | 22.1 ± 3.0; (21) | 61.2 ± 6.0; (67) | 86.9 ± 1.7; (67) | <0.001 | −1,371 | ||
| Serum lactate | 4–4.9 mmol/l | 29.5 ± 1.2; (37) | 19.7 ± 2.6; (23) | 29.7 ± 7.5; (37) | <0.001 | 62.7 ± 3.7; (37) | 0.005 | −1,652 |
| 5–10 mmol/l | 33.6 ± 1.4; (28) | 22.2 ± 4.2; (11) | 53.6 ± 9.4; (28) | 76.9 ± 4.0; (28) | 0.048 | −1,244 | ||
| >10 mmol/l | 37.4 ± 0.8; (49) | 27.9 ± 3.3; (11) | 71.4 ± 6.5; (49) | 86.6 ± 1.9; (49) | 0.085 | −1,029 | ||