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. 2022 Mar 18;13:867937. doi: 10.3389/fimmu.2022.867937

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Copyright © 2022 Underwood, Park, Uebelhoer, Gu, Kunkel, Korthuis, Cook, Sekaly, Ribeiro and Lancioni

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alcohol-use disorder is associated with alterations in cell-surface and soluble CD163 Among PLWH. Soluble CD163 was quantified by ELISA in plasma collected from CTN-055 participants at W0 (A; n = 23) and W4 (B; n = 23) timepoints, and PLWH ref. population (n = 29) at study enrollment. Shown are log2 transformed data, with means and SD. CD163 expression was analyzed on CD14⁺ monocytes using flow cytometry among CTN-055 participants at W0 (n = 21) and W4 (n = 20), and PLWH ref. population (n = 22) at study enrollment; shown are means with SD of total CD14⁺CD163⁺ monocytes (C). *indicates unadjusted p-value.