Table 1.
Baseline clinical features of all patients [Mean ± SD/No (%)].
| Characteristics |
Total (n = 410) |
Lung cancer (n = 282) |
Lung cancer with OSA (n = 128) |
Statistics | P |
|---|---|---|---|---|---|
| Age, year | 59.98 ± 3.22 | 59.53 ± 3.53 | 60.98 ± 2.45 | 1.432* | 0.853 |
| Sex | 6.382† | 0.011 | |||
| Male | 238 (58.0) | 152 (53.9) | 86 (67.2) | ||
| Female | 172 (42.0) | 130 (46.1) | 42 (32.8) | ||
| AHI | 4.35 ± 2.01 | 2.54 ± 2.03 | 9.87 ± 1.98 | 0.637* | 0.001 |
| TNM stage | 11.860† | 0.008 | |||
| I | 129 (31.5) | 95 (33.7) | 34 (26.6) | ||
| II | 147 (35.9) | 102 (36.2) | 45 (35.2) | ||
| III | 83 (20.2) | 45 (16.0) | 38 (29.7) | ||
| IV | 51 (12.4) | 40 (14.2) | 11 (8.5) | ||
| Cancer types | 1.115† | 0.291 | |||
| Small cell carcinoma | 73 (17.8) | 54 (19.1) | 19 (14.8) | ||
| Non-small cell carcinoma | 337 (82.2) | 228 (80.9) | 109 (85.2) | ||
| BMI | 20.88 ± 1.78 | 20.43 ± 1.54 | 21.90 ± 2.98 | 1.445* | 0.384 |
| Hypertension | 128 (31.2) | 84 (29.8) | 44 (34.4) | 0.863† | 0.353 |
| Diabetes | 144 (35.1) | 102 (36.2) | 42 (32.8) | 0.435† | 0.509 |
| Coronary heart disease | 64 (15.6) | 37 (13.1) | 27 (21.2) | 4.249† | 0.039 |
| Heart rate, beats/min | 91.76 ± 20.34 | 91.43 ± 21.54 | 92.34 ± 17.92 | 1.432* | 0.758 |
| KPS | 80.23 ± 12.44 | 82.34 ± 13.54 | 76.34 ± 8.342 | 0.552* | 0.817 |
| Smoking history | 167 (40.7) | 110 (39.0) | 57 (44.5) | 1.113† | 0.292 |
| LSpO2 (%) | 78.32 ± 10.23 | 87.32 ± 15.64 | 69.43 ± 6.31 | 1.954* | 0.009 |
| T90%, min | 56.34 ± 3.41 | 23.43 ± 1.65 | 91.23 ± 4.43 | 1.943* | 0.001 |
| TS90%, % | 9.32 ± 2.01 | 1.32 ± 1.03 | 22.41 ± 2.89 | 3.215* | 0.001 |
| ODI4 | 0.45 ± 0.19 | 0.23 ± 0.08 | 1.98 ± 0.28 | 1.344* | 0.001 |
Data were shown as mean ± standard deviation, n (%).
*
t-test.
†
x2 value.
AHI, apnea hypopnea index; BMI, body mass index; LSpO2 (%), lowest arterial oxygen saturation; T90%, oxygen below 90% of the time; TS90%, the percentage of the total recorded time spend below 90% oxygen saturation; ODI4, oxygen desaturation index.