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. 2022 Mar 18;12:810170. doi: 10.3389/fonc.2022.810170

Table 3.

Univariate Cox analysis (overall and organ metastasis group).

Overall (n = 2072) Organ metastasis group (n = 870)
Factor X2/f P value X2/f P value
Organ metastasis 669.482 P<0.001
Sex 30.833 P<0.001 8.614 P=0.003
Race 2.748 P=0.253 1.180 P=0.554
Primary site 89.510 P<0.001 4.720 P=0.317
Grade 129.045 P<0.001 4.661 P=0.324
Laterality 14.506 P=0.002 3.365 P=0.339
T 345.769 P<0.001 18.45 P=0.002
N 419.014 P<0.001 15.007 P=0.005
M 682.722 P<0.001 3.531 P=0.171
Primary site surgery 603.674 P<0.001 24.512 P<0.001
Radiotherapy + surgery 0.847 P=0.357 29.495 P<0.001
Radiotherapy 20.858 P<0.001 33.700 P<0.001
Chemotherapy 3.692 P=0.055 188.354 P<0.001
Bone metastasis 269.658 P<0.001 7.536 P=0.01
Brain metastasis 168.078 P<0.001 4.739 P=0.059
Liver metastasis 392.654 P<0.001 32.561 P<0.001
Lung metastasis 141.120 P<0.001 1.381 P=0.699
Insurance 9.701 P=0.008 3.724 P=0.155
Marital status
Age
8.654
9.66
P=0.124
P=0.002
10.027
17.28
P=0.074
P<0.001

In the overall sample, sex (P 0.000), primary site (P 0.000), histological grade (P 0.000), laterality (P 0.000), T (P 0.000), N (P 0.000), M (P 0.000), primary site surgery (P 0.000), radiotherapy (P 0.000), insurance (P 0.008), organ metastasis (P 0.000), liver metastasis (P 0.000), brain metastasis (P 0.000), bone metastasis (P 0.000), intrapulmonary metastasis (P 0.000), and age (P 0.002) were all factors affecting survival time.

A total of 870 patients with organ metastasis were analyzed for prognostic factors. By Kaplan–Meier analysis, sex (P 0.003), T (P 0.002), N (P 0.005), primary site surgery (P 0.000), radiotherapy (P 0.000), chemotherapy (P 0.000), age (P 0.000), bone metastasis (P 0.01), and liver metastasis (P 0.000) were all factors affecting survival time.