Table 4.

Multivariate Cox analysis (organ metastasis group and the overall sample).

Group	Factor	B	SE	P	HR	95%CI
Organ metastasis group (n=870)	Sex	-0.256	0.072	0.000	0.774	0.673-0.891
	Age	0.183	0.081	0.025	1.200	1.024-1.407
	Chemotherapy	1.053	0.077	0.000	2.866	2.466-3.331
	Radiotherapy+surgery	0.210	0.098	0.032	1.234	1.018-1.496
	Primary site surgery	0.406	0.172	0.018	1.500	1.071-2.103
	Liver metastasis	-0.382	0.074	0.000	0.683	0.590-0.790
Overall (n=2072)	Age	0.216	0.060	0.000	1.241	1.104-1.396
	Sex	-0.232	0.051	0.000	0.793	0.717-0.877
	Primary site surgery	0.905	0.085	0.000	2.473	2.094-2.920
	Radiotherapy	0.223	0.061	0.000	1.250	1.109-1.409
	Chemotherapy	0.819	0.058	0.000	2.267	2.025-2.539
	Bone metastasis	-0.189	0.073	0.009	0.828	0.718-0.954
	Brain metastasis	-0.329	0.077	0.000	0.720	0.619-0.837
	Liver metastasis	-0.406	0.072	0.000	0.666	0.578-0.767

Organ metastasis group: Multivariate cox regression analysis showed that sex (P 0.000 HR 0.774, 95%CI 0.673–0.891), radiotherapy +surgery (P 0.032 HR 1.234, 95%CI 1.018–1.496), chemotherapy (p 0.000 HR 2.866, 95%CI 2.466–3.331), age (P 0.025 HR 1.200, 95%CI 1.024–1.407), primary site surgery (P 0.018 HR 1.500, 95%CI 1.071–2.103), and liver metastasis (P 0.000 HR 0.683, 95%CI 0.590–0.790) were all independent factors affecting the prognosis.

The overall sample: multivariate Cox regression analysis showed that age (P 0.000 HR 1.241, 95%CI 1.104–1.396), sex (P 0.000 HR 0.793, 95%CI 0.717–0.877), primary site surgery (P 0.000 HR 2.473, 95%CI 2.094–2.920), radiotherapy (P 0.000 HR 1.250, 95%CI 1.109–1.409), chemotherapy (p 0.000 HR 2.267, 95%CI 2.025–2.539), bone metastasis (P 0.009 HR 0.828, 95%CI 0.718–0.954), brain metastasis (P 0.000 HR 0.720, 95%CI 0.619–0.837), and liver metastasis (P 0.000 HR 0.666, 95%CI 0.578–0.767) were all independent factors affecting the prognosis.