Table 3.

Associations of GRSs with PFS and OS of advanced lung adenocarcinoma patients treated with EGFR-TKIs.

GRS	PFS*			OS*
	Events/n	HR (95% CI)	P value	Events/n	HR (95% CI)	P value
low	83/97	1		36/80	1
intermediate	127/142	1.432 (1.082-1.897)	0.012	87/159	1.416 (0.953-2.105)	0.085
high	76/79	2.008 (1.453-2.774)	< 0.001	59/79	2.816 (1.845-4.300)	< 0.001

CI, confidence interval; GRS, genetic risk score; HR, hazard ratio; PFS, progression-free survival; OS, overall survival.

*Adjusted by sex, age, smoking status, ECGO, and TNM stages.