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. 2022 Mar 31;3(2):e127. doi: 10.1002/mco2.127

FIGURE 8.

FIGURE 8

The positive feedback loop of the aging‐ROS‐mitochondrial dysfunction‐ROS axis. Aging generally accompanies ROS overproduction, which contributes to mitochondrial dysfunction via different mechanisms. Notably, mitochondrial dysfunction further induces ROS generation and accelerates aging, suggesting that scavenging ROS could efficiently attenuate aging