Table 4.

The univariate analysis of 5-year survival prognostic factors in lung squamous cell carcinoma patients

Variable	Univariate analysis
	P value＞│z│	HR (95% CI)
Tumour budding (10 HPF)
Low (n=83) vs high (n=49)	0.002*	0.589 (0.423 to 0.820)
Nuclear size
Small (n=129) vs large (n=3)	0.159	0.390 (0.880 to 2.196)
Smallest tumour cell nest
Single cell (n=49) vs 2–4cells (n=77)	0.002*	0.485 (0.307 to 0.769)
Gender
Male (n=94) vs female (n=58)	0.964	1.014 (0.552 to 1.863)
Age (years)
≤65 (n=52) vs＞65 (n=100)	0.908	0.972 (0.600 to 1.575)
Pleural invasion
Absent (n=132) vs present (n=20)	0.001*	0.302 (0.149 to 0.613)
Vascular invasion
Absent (n=62) vs present (n=90)	0.005*	2.397 (1.307 to 4.396)
STAS
Absent (n=75) vs present (n=77)	0.004*	2.426 (1.327 to 4.435)
Necrosis
Absent (n=7) vs present (n=145)	0.287	1.252 (0.828 to 1.896)
Peritumoural space
Absent(n=36) vs present (n=116)	<0.001*	4.389 (1.920 to 10.035)
Interstitial fibrosis
Absent(n=6) vs present (n=146)	0.009*	1.315 (1.071 to 1.614)
pT
pT1 +pT2(n=119) vs pT3 +pT4 (n=33)	<0.001*	2.398 (1.584 to 3.629)
pN
pN0(n=84) vs pN1 +pN2+pN3 (n=68)	0.029*	1.440 (1.038 to 1.999)
TNM stage
Ⅰ+ Ⅱ(n=118)vs Ⅲ+ Ⅳ(n=34)	0.016*	1.954 (1.133 to 3.372)

*P＜0.05

HPF, high-power field; STAS, spread through air spaces; TNM, tumour node metastasis.