Table 1.
Variable | Aphasic stroke | Non-aphasic stroke | Healthy control | Aphasic versus healthy control, P-value | Non-aphasic versus healthy control, P-value | Aphasic versus non-aphasic, P-value | Test (two-tailed) |
---|---|---|---|---|---|---|---|
N | 32 | 59 | 29 | ||||
Token Test at 3 months (mean, SD) | 13 (2) | 16 (0) | 16 (0) | ||||
Sex (N women, %) | 10 (31%) | 23 (39%) | 10 (34%) | 0.79 | 0.68 | 0.46 | χ 2 |
N left-handed | 1 | 3 | 3 | 0.26 | 0.36 | 0.66 | χ 2 |
NIHSS baseline (median, range) | 3 (0–15) | 2 (0–7) | n/a | n/a | n/a | 0.02 | Mann–Whitney Wilcoxon test |
Years of education (mean, SD) | 11.37 (3.58) | 13.1 (3.38) | 14.62 (3.77) | <0.001 | 0.03 | 0.07 | t-test |
Age at 3 months (mean, SD) | 72.46 (8.78) | 65.57 (13.06) | 69.51 (5.39) | 0.12 | 0.05 | <0.001 | t-test |
Total intracranial volume (TIV) at 3 months, ml (mean, SD) | 1505 (170) | 1478 (172) | 1533 (126) | 0.47 | 0.09 | 0.47 | t-test |
Lesion volume at 3 months, ml (mean, SD) | 18 (48) | 7 (14) | n/a | n/a | n/a | 0.21 | t-test |
White matter hyperintensity (WMH) load at 3 months, %TIV (median, range) | 0.34 (0.05–5.01) | 0.43 (0.01–9.36) | 0.42 (0.06–1.56) | 0.48 | 0.18 | 0.76 | t-testa |
Statistical analysis performed on Log(WMH/TIV) values; WMH data available for 26 aphasic, 46 non-aphasic and 25 control participants.