Table 2.

Summary of Pharmacokinetic Parameters After a Single 75 mg Dose of Rimegepant to Healthy Lactating Women (N = 12)

	Sample medium
	Human milk	Plasma
AUC0-lasta	810.1 (22.4)	NA
AUC0-infa	816.1 (22.3)	4,039.9 (17.4)
AUCtaua	798.0 (22.0)	3,811.9 (17.2)
Cmax, ng/mL	169.6 (23.2)	759.2 (23.0)
Cav, ng/mL	34.0 (22.3)	168.3 (17.4)
Tmax, hb	2.0 (1.0, 2.0)	1.4 (1.2, 1.8)
Milk:plasma concentration ratio	0.2 (16.2)

^a ng^*h/mL.

^b Median (range).

Data are geometric mean (% coefficient of variation) unless otherwise noted.

AUC, area under the concentration–time curve; NA, not applicable.