. 2022 Mar 31;5(3):e224427. doi: 10.1001/jamanetworkopen.2022.4427

Table 2. irAE Relative Indexes After Intervention.

irAE index	Patient group, No. (%)^a		χ² value	HR (95% CI)	P value
irAE index	ePRO intervention (n = 141)	Control (n = 137)	χ² value	HR (95% CI)	P value
IrAE occurrence
Yes	111 (78.7)	117 (85.4)	2.101	0.63 (0.34-1.18)	.16
No	30 (21.3)	20 (14.6)	2.101	0.63 (0.34-1.18)	.16
Severe irAE
Yes	29 (20.6)	46 (33.6)	5.969	0.51 (0.30-0.88)	.01
No	112 (79.4)	91 (66.4)	5.969	0.51 (0.30-0.88)	.01
ED visits
Yes	23 (16.3)	41 (29.9)	7.268	0.46 (0.26-0.81)	.01
No	118 (83.7)	96 (70.1)	7.268	0.46 (0.26-0.81)	.01
Treatment discontinuation
Yes	5 (3.6)	15 (11.0)	5.703	0.30 (0.11-0.85)	.02
No	136 (96.5)	122 (89.1)	5.703	0.30 (0.11-0.85)	.02
Death
Yes	2 (1.4)	5 (3.6)	1.409	0.38 (0.07-1.99)	.28
No	139 (98.6)	132 (96.3)	1.409	0.38 (0.07-1.99)	.28

Abbreviations: ED, emergency department; ePRO, electronic patient-reported outcome; HR, hazard ratio; irAE, immune-related adverse event.

^{^a}

Percentages have been rounded and may not total 100.