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CC50, EC50, and SI values for ATV in Vero E6 and Caco-2 cells infected with SARS-CoV-2.
| Compound | Cell line | CC50 (μM) | Virus | Treatment strategy | EC50 (μM) | IS |
|---|---|---|---|---|---|---|
| Atorvastatin | Vero E6 | 50.3 | D614G strain | Pre-post treatment | 15.4 | 3.3 |
| Pre-infection treatment | 12.1 | 4.2 | ||||
| Post-infection treatment | 11.1 | 4.5 | ||||
| Delta variant | Pre-post treatment | 16.8 | 3.0 | |||
| Mu variant | Pre-post treatment | 21.1 | 2.4 | |||
| Caco-2 | 64.5 | D614G strain | Pre-post treatment | 7.4 | 8.7 |
