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. 2022 Apr;162(4):1197–1209.e13. doi: 10.1053/j.gastro.2021.12.271

Supplementary Methods Figure 1.

Supplementary Methods Figure 1

H&E and IHC workflow using specific antibodies to identify gland phenotypes. H&E is the primary histologic guide. Only intestinal glands do not express MUC5AC; however, glands transitioning from specialized to a mature intestinal phenotype may have weak MUC5AC (MUC5AClo) staining and are considered specialized. -ve, negative; +ve, positive.