Table 3:
Patient/Group | PET hypometabolism | PET laterality | MRI MTS | MRI TPa | MRI AL | Lesion Location | Pathology | Pathology MTS | |||
---|---|---|---|---|---|---|---|---|---|---|---|
NR1 | NR2 | NR1 | NR2 | NR1 | NR2 | ||||||
1 – A | Y | R | - | _ | - | - | - | + | R amygdala enlargement | FCDIIa | No |
2 – A | Y | BL | - | _ | - | - | - | + | L amygdala enlargement | FCDIb | No |
3 – A | Y | L | L | L | - | - | - | - | - | FCDIIa | No |
4 – A | N/A | N/A | - | _ | - | - | + | + | R amygdala, periamygdaloid and temporal piriform cortex, hippocampal head | DNT | No |
5 – A | Y | R | R | R | R | R | - | - | - | FND | Yes |
6 – A | Y | L | - | _ | L | L | - | + | L amygdala and hippocampal head | FCDIb | No |
7 – A | Y | L | L | L | - | - | + | + | L PHG | FCDIIIa | Yes |
8 – B | Y | R | - | _ | - | - | + | + | R fusiform gyrus | GG; FCDIIIb | No |
9 – B | Y | L | L | L | - | L | - | - | Left hippocampal sclerosis | None | Yes |
10 – B | Y | L | L | L | - | - | - | - | Left hippocampal sclerosis | None | Yes |
Neuroimaging and pathology findings in all study patients. Group A are patients 1–7 and Group B are patients 8–10. MRI findings of MTS, temporal pole abnormalities, or anatomical lesions are denoted as either R, L, or BL (if present, with R, L, or BL denoting Right, Left, or Bilateral, respectively) or – (not present). One MRI interpretation is provided for each patient by two different neuroradiologists. NR1 and NR2 denotes which neuroradiologist interpretation is depicted. TPa: Temporal pole abnormalities. MRI AL: Anatomical lesion on MR imaging. FCD: Focal cortical dysplasia. DNT: Dysembryoplastic neuroepithelial tumor. FND: Focal nodular dysplasia. GG: Ganglioglioma.