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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Pediatr Rev. 2021 Feb;42(2):55–67. doi: 10.1542/pir.2019-0212

Figure 1.

Figure 1.

Cystic fibrosis transmembrane conductance regulator (CFTR) mutation classes. CFTR mutations have been grouped into 6 distinct classes based on abnormalities of CFTR synthesis, structure, and function. Reprinted with from: Boyle MP, DeBoeck K. A new era in the treatment of cystic fibrosis: correction of the underlying CFTR defect. Lancet Respir Med. 2013;1(2):158–163.