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. 2022 Mar 30;221(5):e202107016. doi: 10.1083/jcb.202107016

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© 2022 Flores et al.

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Figure S1. — Distributions of rupture force for couplers based on wild-type and mutant Ndc80 complexes, displayed as Kaplan-Meier survival curves. (A–C) Kaplan–Meier survival curves comparing wild-type Ndc80 complex versus Ndc80 mutants that disrupt region A^Ndc80p (A), region B^Ndc80p (B), and region C^Ndc80p (C). Solid curves were measured with Ndc80 complex–decorated beads alone, in the absence of free Dam1 complex. Dashed curves were measured in the presence of 30 nM wild-type Dam1 complex in solution. A single dataset recorded with wild-type Ndc80 complex is shown on all three graphs for comparison.