Table 1.

Definition of the primary outcome in the studies included in the meta-analysis

Author [Ref], year	Definition of clinical improvement/treatment success
Abu Dayyeh, 2018	Resolution of WON without concomitant percutaneous drainage
Bang, 2019	Resolution of WON on CT scan in association with clinical resolution of symptoms at 6-month follow-up.
Bapaye, 2017	Symptom resolution and complete WON resolution on imaging at the end of the treatment period
Chen, 2019	Decrease of WON > 3 cm in 6 months without need for percutaneous drainage or surgery
Faisal, 2018	Complete collection resolution
Ge, 2018	Successful resolution of the WON
Mukai, 2015	Disappearance of symptoms or inflammation regardless of the collection size
Sahar, 2017	Ability to remove the percutaneous drain once the necrotic cavity had resolved as confirmed by CT scan without recurrence of fluid collection over the ensuing 4 weeks.
Siddiqui, 2017	Complete resolution of the WON cavity and resolution of the patient’s symptoms without need for reintervention at 6 months after the initial treatment, as seen on ambulatory clinic follow-up and cross-sectional imaging

CT, computed tomography; WON, walled-off necrosis.