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. 2022 Mar 18;14(12):14025–14032. doi: 10.1021/acsami.1c22439

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(a) Representative correlation curve measured by FCS (black) on a solution containing SARS-CoV-2 particles exposed to 5 nM Hyp. The red line shows the results of the fitting with a model comprising a single diffusing species. (b) Integrated fluorescence emission of Hyp, at increasing concentration, in the presence of the same amount of SARS-CoV-2 particles (black circles). The red line shows the result of the fitting with a binding model. (c) Normalized time-resolved fluorescence decays observed for Hyp bound to DLPC liposomes (black) and SARS-CoV-2 particles (red). The green lines show the results of the fitting with a biexponential model for both decays.