Table 1:
Pooled estimates of baseline characteristics of AD-A and AD-B patients
| Variables | AD-A |
AD-A + AD-B |
AD-B |
Significant | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Males, pooled estimate (95% CI) | Females, pooled estimate (95% CI) | OR/SMD (95% CI) | P-value | Studies | I 2 (%) | Males, pooled estimate (95% CI) | Females, pooled estimate (95% CI) | OR/SMD (95% CI) | P-value | Studies | I 2 (%) | Males | Females | ||
| Age (mean) | 59.6 | 67.7 | −0.62 | <0.001 | 9 | 80.4 | 53.6 | 58.5 | −0.39 | <0.001 | 3 | 15.2 | 62.8 | 69.8 | [25] (1/1) |
| (58.5–60.7) | (65.4–70.0) | (−0.77 to −0.48)a | (47.4–60.6) | (50.5–67.7) | (−0.49 to 0.30)a | ||||||||||
| Mean BSA (m2) | 1.99 | 1.59 | 0.79 | 0.016 | 3 | 96.3 | - | - | - | - | - | - | - | - | - |
| (1.83–2.15) | (1.37–1.84) | (0.15–1.44)a | |||||||||||||
| Mean BMI (kg/m2) | 26.0 | 25.1 | 0.23 | 0.040 | 5 | 80.0 | 25.9 | 25.3 | - | - | 1 | - | - | - | - |
| (25.1–26.9) | (23.4–26.8) | (0.01–0.45)a | |||||||||||||
| History of hypertension (%) | 69.6 | 76.0 | 0.78 | 0.052 | 7 | 44.5 | 74.5 | 75.6 | 0.93 | 0.693 | 3 | 55.6 | 78.9 | 79.2 | [25] (0/1) |
| (58.7–82.5) | (68.5–84.3) | (0.60–1.00)b | (67.3–82.5) | (72.4–78.9) | (0.67–1.31)b | ||||||||||
| Diabetes mellitus (%) | 5.35 | 6.30 | 0.89 | 0.700 | 7 | 60.3 | 7.10 | 7.24 | 0.98 | 0.958 | 3 | 60.7 | 14.8 | 18.0 | [25] (1/1) |
| (3.15–9.08) | (4.33–9.16) | (0.50–1.60)b | (2.17–23.2) | (4.32–12.2) | (0.54–1.79)b | ||||||||||
| Hyperlipidaemia (%) | 14.4 | 16.0 | 0.94 | 0.615 | 5 | 11.0 | - | - | - | - | - | - | - | - | - |
| (9.50–21.7) | (12.0–21.4) | (0.73–1.20)b | |||||||||||||
| Smoking (%) | 39.5 | 14.4 | 4.27 | 0.077 | 4 | 97.1 | 61.6 | 9.22 | 15.1 | <0.001 | 2 | 74.5 | - | - | - |
| (23.5–66.3) | (6.39–32.5) | (0.85–21.4)b | (51.5–73.7) | (2.27–37.4) | (5.18–43.8)b | ||||||||||
| COPD (%) | 6.24 | 7.98 | 0.74 | 0.138 | 5 | 18.8 | - | - | - | - | - | - | 21.4 | 26.2 | [25] (1/1) |
| (4.00–9.75) | (5.61–11.4) | (0.49–1.10)b | |||||||||||||
| History of cerebrovascular disease (%) | 6.88 | 9.30 | 0.85 | 0.559 | 3 | 33.7 | - | - | - | - | - | - | - | - | - |
| (2.65–17.8) | (4.17–20.8) | (0.49–1.47)b | |||||||||||||
| Chronic kidney disease (%) | 8.26 | 7.24 | 1.38 | 0.224 | 5 | 46.1 | - | - | - | - | - | - | - | - | - |
| (2.84–24.0) | (3.35–15.7) | (0.82–2.33)b | |||||||||||||
| Congestive heart failure (%) | - | - | - | - | - | - | 3.39 | 4.26 | 0.70 | 0.199 | 3 | 15.1 | 17.9 | 20.4 | [25] (1/1) |
| (2.12–5.45) | (1.60–11.3) | (0.41–1.20)b | |||||||||||||
| Marfan syndrome (%) | 4.12 | 2.67 | 1.57 | 0.007 | 5 | 2.11 | 3.48 | 2.88 | 1.37 | 0.300 | 2 | 0.0 | - | - | - |
| (3.34–5.07) | (1.87–3.82) | (1.13–2.19)b | (1.33–9.11) | (0.91–9.12) | (0.75–2.50)b | ||||||||||
| Bicuspid aortic valve (%) | - | - | - | - | - | - | 3.07 | 3.92 | 0.80 | 0.615 | 2 | 10.0 | - | - | - |
| (2.03–4.63) | (2.06–7.47) | (0.34–1.88)b | |||||||||||||
| Previous aortic aneurysm (%) | - | - | - | - | - | - | 18.9 | 14.5 | 1.23 | 0.256 | 2 | 18.5 | - | - | - |
| (10.4–34.4) | (10.9–19.3) | (0.86–1.77)b | |||||||||||||
| Previous aortic dissection (%) | - | - | - | - | - | - | 3.26 | 2.94 | 1.33 | 0.341 | 2 | 0.0 | - | - | - |
| (0.99–10.7) | (0.85–10.2) | (0.74–2.38)b | |||||||||||||
‘-’ indicates the variable was not reported in any of the included studies.
a
SMD.
b
OR.
AD-A: acute type A aortic dissection; AD-B: acute type B aortic dissection; BMI: body mass index; BSA: body surface area; CI: confidence interval; COPD: chronic obstructive pulmonary disease; OR: odds ratio; SMD: standardized mean difference.