Table 2:
Pooled estimates of patient presentation of AD-A and AD-B patients
| Variables | AD-A |
AD-A + AD-B |
AD-B |
Significant | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Males, pooled estimate (95% CI) | Females, pooled estimate (95% CI) | OR/SMD (95% CI) | P-value | Studies | I 2 (%) | Males, pooled estimate (95% CI) | Females, pooled estimate (95% CI) | OR/SMD (95% CI) | P-value | Studies | I 2 (%) | Males | Females | ||
| Hypotension/shock at presentation (%) | 17.6 | 19.6 | 0.86 | 0.136 | 5 | 0.0 | 6.07 | 3.97 | 1.24 | 0.685 | 2 | 33.6 | 4.93 | 4.31 | [25] (0/1) |
| (11.7–26.6) | (13.7–28.0) | (0.7–1.05)a | (2.38–15.5) | (0.46–34.3) | (0.44–3.44)a | ||||||||||
| Tamponade (%) | 19.4 | 21.9 | 0.87 | 0.042 | 4 | 0.0 | - | - | - | - | - | - | - | - | - |
| (15.2–24.8) | (19.2–25.0) | (0.75–0.99)a | |||||||||||||
| Pericardial effusion (%) | 33.0 | 42.5 | 0.70 | 0.436 | 2 | 78.7 | 20.8 | 30.8 | 0.61 | <0.001 | 3 | 0.0 | - | - | - |
| (16.9–64.3) | (35.4–50.9) | (0.29–1.71)a | (15.3–28.4) | (22.6–42.0) | (0.50–0.75)a | ||||||||||
| Cerebral ischaemia (%) | 8.87 | 11.3 | 0.91 | 0.350 | 3 | 0.87 | - | - | - | - | - | - | - | - | - |
| (5.33–14.8) | (7.94–16.2) | (0.74–1.11)a | |||||||||||||
| Presentation ≥24 h (%) | - | - | - | - | - | - | 39.4 | 45.7 | 0.74 | 0.024 | 2 | 3.94 | - | - | - |
| (13.9–112.1) | (20.5–101.9) | (0.58–0.96)a | |||||||||||||
| Abrupt onset of pain (%) | - | - | - | - | - | - | 87.5 | 86.4 | 0.78 | 0.791 | 2 | 88.8 | - | - | - |
| (84.1–91.0) | (68.9–108.4) | (0.12–4.97)a | |||||||||||||
| Chest pain (%) | - | - | - | - | - | - | 78.3 | 77.9 | 1.07 | 0.646 | 3 | 32.8 | - | - | - |
| (73.3–83.5) | (71.3–85.2) | (0.81–1.41)a | |||||||||||||
| Back pain (%) | - | - | - | - | - | - | 57.5 | 58.6 | 0.95 | 0.760 | 3 | 61.8 | - | - | - |
| (52.9–62.6) | (48.6–70.8) | (0.69–1.31)a | |||||||||||||
| Abdominal pain (%) | - | - | - | - | - | - | 18.4 | 15.8 | 1.22 | 0.462 | 2 | 51.7 | - | - | - |
| (13.9–24.4) | (7.65–32.8) | (0.72–2.05)a | |||||||||||||
| Any focal neurological deficits (%) | - | - | - | - | - | - | 11.4 | 6.31 | 1.74 | 0.481 | 2 | 77.4 | - | - | - |
| (7.38–17.7) | (0.92–43.1) | (0.37–8.19)a | |||||||||||||
| Syncope (%) | - | - | - | - | - | - | 3.06 | 4.54 | 0.86 | 0.440 | 2 | 0.0 | - | - | - |
| (0.18–52.5) | (0.38–54.8) | (0.59–1.26)a | |||||||||||||
| Altered consciousness/ coma (%) | - | - | - | - | - | - | 8.07 | 11.9 | 0.66 | 0.012 | 2 | 0.0 | - | - | - |
| (6.76–9.63) | (9.47–14.9) | (0.48–0.91)a | |||||||||||||
| Pulse deficit (%) | - | - | - | - | - | - | 22.4 | 12.6 | 1.99 | <0.001 | 2 | 0.0 | - | - | - |
| (14.6–34.5) | (6.57–24.2) | (1.47–2.69)a | |||||||||||||
| Mean creatinine (mg/dl) | 1.23 | 0.97 | 0.38 | <0.001 | 5 | 73.4 | - | - | - | - | - | - | - | - | - |
| (1.12–1.34) | (0.87–1.07) | (0.20–0.56)b | |||||||||||||
| Renal insufficiency (%) | – | – | – | – | – | – | – | – | – | 23.6 | 19.9 | [25] (1/1) | |||
| DeBakey type II (%) | 14.3 | 23.3 | 0.57 | <0.001 | 4 | 0.0 | - | - | - | - | - | - | - | - | - |
| (9.18–22.2) | (16.7–32.5) | (0.46–0.70)a | |||||||||||||
| Max. diameter ascending aorta (mm), mean | 54.4 | 53.4 | 0.06 | 0.654 | 2 | 0.0 | - | - | - | - | - | - | - | - | - |
| (51.4–57.5) | (51.1–55.8) | (−0.20 to 0.32)b | |||||||||||||
| Aortic regurgitation (%) | 27.7 | 25.6 | 1.09 | 0.211 | 5 | 0.0 | - | - | - | - | - | - | - | - | - |
| (18.4–41.6) | (15.9–41.2) | (0.95–1.24)a | |||||||||||||
‘-’ indicates the variable was not reported in any of the included studies.
a
OR.
b
SMD.
AD-A: acute type A aortic dissection; AD-B: acute type B aortic dissection; CI: confidence interval; OR: odds ratio; SMD: standardized mean difference.