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. 2018 Jul 19;21(1):50–68. doi: 10.1093/biostatistics/kxy028

Fig. 2.

Fig. 2.

Histogram of point estimates (i.e. posterior means) of the treatment effects Inline graphic and smooth posterior estimates Inline graphic of the treatment effect distribution. The histogram is constructed using all point estimates from both the SOLVD treatment and prevention trials. Smooth estimates, Inline graphic, of the distribution of treatment effects were computed as described in equation (3.5) for the two trials separately. The kernel bandwidth Inline graphic for each trial was chosen using the rule Inline graphic, where Inline graphic and Inline graphic are posterior means of the standard deviation and inter-quartile range of Inline graphic respectively and where Inline graphic is the trial-specific sample size.