Background:
Risk factors for cardiovascular (CV) complications in patients infected with the Coronavirus Disease 2019 (COVID-19) are not well established. We aim to correlate CV comorbidities with the development of CV complications and death in patients hospitalized for COVID-19.
Methods:
This is a retrospective analysis of 650 patients hospitalized for COVID-19. Chart review was performed to ascertain pre-existing CV comorbidities and determine subsequent CV complications and mortality.
Results:
CV comorbidities, including hypertension (81%, p<0.001), cardiac disease (50.3%, p<0.001), diabetes (44.7%, p=0.04), QTc prolongation (16.8%, p=0.04), and stroke (14.4%, p=0.003), significantly predisposed patients to CV complications compared to no CV complications development (88.9% vs. 74.6%, p<0.001). Non-CV comorbidities predisposing patients to CV complications include kidney disease (22.4%, p=0.01), chronic hematologic disorder (11.2%, p=0.009), end stage renal disease (10.1%, p=0.001), and dialysis (7.3%, p=0.009). Pre-existing CV comorbidities did not alter 30-day survival rates while CV complications significantly lowered 30-day survival probability (p<0.001). Cardiac arrest (90.8%), arrhythmia (42.7%), myocardial infarction (40.7%), and deep vein thrombosis (38.2%) were CV complications strongly associated with mortality.
Conclusion:
Patients with pre-existing CV comorbidities are more likely to develop CV complications during hospitalization with COVID-19.
Footnotes
Poster Contributions
For exact presentation time, refer to the online ACC.22 Program Planner at https://www.abstractsonline.com/pp8/#!/10461
Session Title: Spotlight on Special Topics Flatboard Poster Selections: COVID
Abstract Category: 61. Spotlight on Special Topics: Coronavirus Disease (COVID-19)