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Treatment-Associated AEs and Incidence
| Treatment-associated AEs | HA filling plus mesotherapy combined treatment group, n (%) | BTX-A treatment group, n (%) | P value |
|---|---|---|---|
| Lumps | 2 (8) | — | — |
| Erythema | 25 (100) | 22 (95.7) | 0.479 |
| Topical edema and swelling | 25 (100) | 2 (8.7) | 0.000 |
| Ecchymosis | 14 (56) | 7 (30.4) | 0.074 |
| Tyndall effect | 2 (8) | — | — |
| Trachyphonia | — | 1 (4.3) | — |
| Rashes and itchiness | 3 (12) | — | — |
AE, adverse event; BTX-A, botulinum toxin A; HA, hyaluronic acid.
