Table 1.
Characteristic | No. of patients (n = 1,165) | Polyp recurrence (n = 531) | Univariate |
Multivariate |
||
---|---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |||
Age | ||||||
<50 years | 447 | 167 (37.4) | 1 | 1 | ||
≥50 years | 718 | 364 (50.7) | 1.72 (1.36–2.19) | <0.01 | 1.70 (1.31–2.20) | <0.01 |
Gender | ||||||
Female | 426 | 149 (35.0) | 1 | 1 | ||
Male | 739 | 382 (51.7) | 1.99 (1.56–2.54) | <0.01 | 1.42 (1.07–1.90) | 0.02 |
Body mass index | ||||||
<24 kg/m2 | 668 | 264 (39.5) | 1 | 1 | ||
≥24 kg/m2 | 497 | 267 (53.7) | 1.78 (1.41–2.25) | <0.01 | 1.59 (1.23–2.04) | <0.01 |
Number of polyps | ||||||
<3 | 919 | 366 (39.8) | 1 | 1 | ||
≥3 | 246 | 165 (67.1) | 3.08 (2.29–4.14) | <0.01 | 1.97 (1.34–2.90) | 0.01 |
Anatomical location | ||||||
Proximal colon | 369 | 177 (48.0) | 1 | |||
Distal colon | 496 | 228 (46.0) | 0.92 (0.70–1.21) | 0.56 | ||
Rectum | 300 | 126 (42.0) | 0.79 (0.58–1.07) | 0.12 | ||
Size | ||||||
<10 mm | 907 | 415 (45.8) | 1 | |||
≥10 mm | 258 | 116 (45.0) | 0.97 (0.73–1.28) | 0.97 | ||
Pathological type | ||||||
Serrated polyps | 385 | 177 (46.0) | 1 | |||
Conventional adenomas | 780 | 354 (45.4) | 0.98 (0.76–1.25) | 0.98 | ||
Coexistence of adenomas and serrated polyps | ||||||
No | 1,053 | 461 (43.8) | 1 | 1 | ||
Yes | 112 | 70 (62.5) | 2.14 (1.43–3.20) | <0.01 | 1.28 (0.81–2.02) | 0.28 |
High-grade dysplasia | ||||||
No | 1,053 | 479 (45.5) | 1 | |||
Yes | 112 | 52 (46.4) | 1.04 (0.70–1.54) | 0.85 | ||
Smoker status | ||||||
Never | 909 | 373 (41.0) | 1 | 1 | ||
Current | 256 | 158 (61.7) | 2.32 (1.74–3.08) | <0.01 | 1.52 (1.09–2.13) | 0.01 |
Alcohol consumption | ||||||
Never | 1,086 | 476 (43.8) | 1 | 1 | ||
Current | 79 | 55 (69.6) | 2.94 (1.79–4.81) | <0.01 | 1.84 (1.08–3.16) | 0.03 |
History of hypertension | ||||||
No | 916 | 393 (42.9) | 1 | 1 | ||
Yes | 249 | 138 (55.4) | 1.65 (1.25–2.19) | <0.01 | 1.20 (0.87–1.64) | 0.26 |
History of diabetes | ||||||
No | 1,105 | 493 (44.6) | 1 | 1 | ||
Yes | 60 | 38 (63.3) | 2.14 (1.25–3.67) | 0.01 | 1.47 (0.83–2.63) | 0.19 |
Family history of polyps | ||||||
No | 1,068 | 476 (44.6) | 1 | 1 | ||
Yes | 97 | 55 (56.7) | 1.63 (1.07–2.48) | 0.02 | 1.65 (1.06–2.59) | 0.03 |
Family history of CRC | ||||||
No | 1,095 | 486 (44.4) | 1 | 1 | ||
Yes | 70 | 45 (64.3) | 2.26 (1.36–3.73) | 0.01 | 2.15 (1.26–3.67) | 0.01 |
OR, odds ratio; CI, confidence interval; CRC, colorectal cancer.