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. 2021 Sep 16;10:goab038. doi: 10.1093/gastro/goab038

Table 1.

Univariate and multivariate logistic-regression analysis on risk factors for polyp recurrence

Characteristic No. of patients (n = 1,165) Polyp recurrence (n = 531) Univariate
Multivariate
OR (95% CI) P-value OR (95% CI) P-value
Age
 <50 years 447 167 (37.4) 1 1
 ≥50 years 718 364 (50.7) 1.72 (1.36–2.19) <0.01 1.70 (1.31–2.20) <0.01
Gender
 Female 426 149 (35.0) 1 1
 Male 739 382 (51.7) 1.99 (1.56–2.54) <0.01 1.42 (1.07–1.90) 0.02
Body mass index
 <24 kg/m2 668 264 (39.5) 1 1
 ≥24 kg/m2 497 267 (53.7) 1.78 (1.41–2.25) <0.01 1.59 (1.23–2.04) <0.01
Number of polyps
 <3 919 366 (39.8) 1 1
 ≥3 246 165 (67.1) 3.08 (2.29–4.14) <0.01 1.97 (1.34–2.90) 0.01
Anatomical location
 Proximal colon 369 177 (48.0) 1
 Distal colon 496 228 (46.0) 0.92 (0.70–1.21) 0.56
 Rectum 300 126 (42.0) 0.79 (0.58–1.07) 0.12
Size
 <10 mm 907 415 (45.8) 1
 ≥10 mm 258 116 (45.0) 0.97 (0.73–1.28) 0.97
Pathological type
 Serrated polyps 385 177 (46.0) 1
 Conventional adenomas 780 354 (45.4) 0.98 (0.76–1.25) 0.98
Coexistence of adenomas and serrated polyps
 No 1,053 461 (43.8) 1 1
 Yes 112 70 (62.5) 2.14 (1.43–3.20) <0.01 1.28 (0.81–2.02) 0.28
High-grade dysplasia
 No 1,053 479 (45.5) 1
 Yes 112 52 (46.4) 1.04 (0.70–1.54) 0.85
Smoker status
 Never 909 373 (41.0) 1 1
 Current 256 158 (61.7) 2.32 (1.74–3.08) <0.01 1.52 (1.09–2.13) 0.01
Alcohol consumption
 Never 1,086 476 (43.8) 1 1
 Current 79 55 (69.6) 2.94 (1.79–4.81) <0.01 1.84 (1.08–3.16) 0.03
History of hypertension
 No 916 393 (42.9) 1 1
 Yes 249 138 (55.4) 1.65 (1.25–2.19) <0.01 1.20 (0.87–1.64) 0.26
History of diabetes
 No 1,105 493 (44.6) 1 1
 Yes 60 38 (63.3) 2.14 (1.25–3.67) 0.01 1.47 (0.83–2.63) 0.19
Family history of polyps
 No 1,068 476 (44.6) 1 1
 Yes 97 55 (56.7) 1.63 (1.07–2.48) 0.02 1.65 (1.06–2.59) 0.03
Family history of CRC
 No 1,095 486 (44.4) 1 1
 Yes 70 45 (64.3) 2.26 (1.36–3.73) 0.01 2.15 (1.26–3.67) 0.01

OR, odds ratio; CI, confidence interval; CRC, colorectal cancer.