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. 2022 Mar 18;13:868893. doi: 10.3389/fendo.2022.868893

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Copyright © 2022 Song, Pan, Chen and Jin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptomic studies of macrophages treated with NPVs. (A) Differentially expressed genes in the transcriptomes of LPS group (left) and LPS+NPVs group (right) (n = 7, the screened differential genes were consistent with |log2FC| > 0.5, p < 0.05). (B) PCA analysis depicted that the LPS group (L) and the LPS+NPVs group (N) were significantly different in space. (C) Volcano plot showing upregulation of TGF-β pathway-related genes after NPS-treated macrophages. (Marked genes are significantly different, p < 0.05).