Table 1. Effect of Cannabinoid Receptor Midulators on miRNA and Hallmark of Cancer.

cannabinoid receptor modulator	effected miRNA	effected hallmark of cancer	ref
CBD	Downregulation of hsa-let-7a	Increased cell death in neuroblastoma	(12)
WIN	Upregulation of miRNA-29b1	Decreased invasion and metastasis in osteosarcoma	(13)
WIN	Downregulation of miRNA-27a	Inhibition of cancer cell growth and apoptosis induction in colon cancer	(14)
CBD	Upregulation of hsa-miRNA-1972	Inhibition of replicative immortality in neuroblastoma	(12)
Betulinic acid	Downregulation of miRNA-27a	Increased cell death in breast cancer	(15)