Table 3. Effect of Cannabinoids on miRNA and Inflammation.
cannabinoid | effect on miRNA | effect on inflammation | ref |
---|---|---|---|
Δ9-THC | Downregulation of miRNA-17, miRNA-92, miRNA-421, and miRNA-374b | Increased inflammation | (24) |
CBD | Downregulation of miRNA-146a, miRNA-34a and miRNA-155 | Decreased inflammation | (26) |
CBD | Upregulation of miRNA-34a | Decreased inflammation | (26) |
Anandamide | Downregulation of miRNA-23a-3p, miRNA-34a-5p | Decreased inflammation | (27) |
Anandamide | Upregulation of miRNA-125a-5p, miRNA-301a, miRNA-30e, and miRNA-151 | Decreased inflammation | (28) |