Table 10. Pharmacokinetics of Synthesized Compounds.

code	GI absorption	BBB permeant	P-gp substrate	CYP1A2 inhibitor	CYP2C19 inhibitor	CYP2C9 inhibitor	CYP2D6 inhibitor	CYP3A4 inhibitor	log Kp cm/s
1	high	yes	no	yes	yes	no	no	no	–5.12
2	high	yes	no	yes	yes	no	yes	yes	–5.63