TABLE 3.

Patient financial data

Variable	Patients, no. (%) (n = 71)	COSTa (mean ± SD)	p-valueb
Annual out-of-pocket expenses (mean ± SD), USD	709 ± 626	24.79 ± 11.49
Annual OOPE:Earnings at time of diagnosis,c median (range)	1.32% (0%−35%)	24.78 ± 11.57
Annual OOPE:Earnings at time of survey,c median (range)	1.59% (0%−25%)	24.97 ± 11.48
Earnings at time of diagnosisc
Less than $10 000	6 (8.5%)	22.83 ± 12.55	0.012
$10 000–$19 999	10 (14.1%)	20.63 ± 14.04
$20 000–$39 999	18 (25.4%)	19.00 ± 10.83
$40 000–$59 999	11 (15.5%)	25.18 ± 10.57
$60 000–$79 999	10 (14.1%)	27.10 ± 8.21
$80 000–$99 999	2 (2.8%)	40.00 ± 5.66
$100 000–$150 000	10 (14.1%)	29.30 ± 10.78
Over $150 000	3 (4.2%)	38.00 ± 2.65
Earnings at time of surveyc
Less than $10 000	11 (15.5%)	12.82 ± 9.11	<0.001
$10 000–$19 999	12 (16.9%)	20.10 ± 13.55
$20 000–$39 999	22 (31.0%)	23.50 ± 8.90
$40 000–$59 999	11 (15.5%)	31.20 ± 6.51
$60 000–$79 999	4 (5.6%)	35.50 ± 4.44
$80 000–$99 999	1 (1.4%)	43
$100 000–$150 000	7 (9.9%)	34.71 ± 3.77
Over $150 000	2 (2.8%)	37.00 ± 2.83
Earning change from diagnosis to time of surveyc
Negative change	28 (39.4%)	21.25 ± 12.37	0.028
No/positive change	43 (60.6%)	27.28 ± 10.26

Abbreviations: COST, comprehensive score for financial toxicity; OOPE, out-of-pocket expenses; SD, standard deviation.

^aLower COST scores represent higher toxicity.

^bKruskal–Wallis test.

^cEarnings data reflects gross/pre-tax annual earnings at the respective time-point.