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. 2022 Mar 18;10:855755. doi: 10.3389/fbioe.2022.855755

TABLE 1.

Overview of drugs and investigational compounds used with IMD platform for multiplex in situ drug response screen.

Minocycline Donepezil Riluzole SAHA ABAH Paclitaxel
Tetracycline antibiotic inhibitor of acetylcholinesterase (AChE) Glutamate inhibitor.NMDA receptor inhibitor HDAC inhibitor Myeloperoxidase inhibitor Microtubule polymer stabilizer
P7C3 Sulfasalazine Etomoxir Buthionine Sulfoximine (BSO) AGI-25696 SnMP(Tin mesoporhyrin)
Neuroprotective chemical that targets NAMPT Inhibitor of NF-kB,TGF-β and COX-2 Inhibitor of carnitine palmitoyltransferase-1 Depletes cellular glutathione levels Methionine adenosyltransferase 2A(MATA2) inhibitor Inhibitor of heme oxidation