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. 2022 Mar 30;60(1):729–742. doi: 10.1080/13880209.2022.2046111

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — β-HIVS ameliorates LPS-induced mouse sepsis. (A) Survival rates of mice. *p < 0.05 vs. the LPS alone group. (B) The levels of TNF-α and IL-1β in serum. (C) The mRNA expression of TNF-α and IL-1β detected in lung tissues. (D) The levels of TNF-α and IL-1β detected in BALF. (E) The percentage of F4/80⁺ CD86⁺ M1 alveolar macrophages and F4/80⁺ CD206⁺ M2 alveolar macrophages in BALF was analyzed by flow cytometry. (F) The lung tissue sections with H&E staining. Original magnification, ×200. ^#p < 0.05 and *p < 0.05 vs. the control and LPS alone groups, respectively.